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LETTER TO THE EDITOR The transition from pediatric to adult services Fernando Coelho das Neves
Dear Editor, It was a very welcome surprise to see another two renal units (Hospital Curry Cabral and Hospital Dona Estefânia, both in Lisbon) initiating pediatric-to-adult nephrology programs.
Port J Nephrol Hypert 2019; 33(1): 87-76 Advance Access publication 29 March 2019 DOWNLOAD PDF
CASE REPORT The oncogenic effect of hepatitis C lasts beyond the disease's eradication Sofia Cerqueira, Catarina Teixeira, Nuno Afonso, Rui Castro, Teresa Morgado, Professor Rui Alves
Hepatitis C virus (HCV) is widely prevalent worldwide, with an estimated 180 million people infected. Its manifestations are not limited to hepatic disease, as it has widely known immunomodulator and oncogenic effects.
Port J Nephrol Hypert 2019; 33(3): 143-144 Advance Access publication 5 September 2019 DOWNLOAD PDF
PERSPECTIVE Renal lithiasis from a nephrologist's perspective Adelaide Serra
Man has known urinary lithiasis since antiquity.
Port J Nephrol Hypert 2019; 33(1): 27-30 Advance Access publication 1 March 2019 DOWNLOAD PDF
REVIEW ARTICLE Current guidelines in peritoneal dialysis - Part I Ana Carina Ferreira, Joana Santos, Manuel Amoedo, Ana Oliveira, Rui Silva, Anabela Malho Guedes, on Behalf of the Peritoneal Dialysis? Study Group of the Portuguese Society of Nephrology (annex 1)
A successful peritoneal dialysis program follows evidence-based practice guidelines.
Port J Nephrol Hypert 2019; 33(1): 19-26 Advance Access publication 1 March 2019 DOWNLOAD PDF
CASE REPORT Recurrence of oxalate nephropathy after renal transplantation in a patient with polyarteritis nodosa: a case report Luís Mendonça, Manuela Bustorf, Roberto Silva, Joana Sobrinho Simões, Susana Sampaio
Hyperoxaluria is an important complication of short bowel syndrome (SBS) and a non‑negligible cause of chronic kidney disease (CKD)  
Port J Nephrol Hypert 2019; 33(1): 31-34 Advance Access publication 14 March 2019 DOWNLOAD PDF
CASE REPORT Endogenous endophthalmitis: a not so rare ophthalmic emergency among hemodialysis patients Andreia Dias da Silva, Luísa Costa, Ana Rodrigues, Carolina Ferreira, Rosa Miguel, Marta Costa, Miguel Oliveira, Tiago Barra, Cátia Pêgo, Giovanni Sorbo, Carla Lima, Jesús Garrido, Tânia Sousa, Edgar
Endogenous endophthalmitis is an intraocular infection secondary to the hematogenous spread of microorganisms.
Port J Nephrol Hypert 2019; 33(1): 57-59 Advance Access publication 27 March 2019 DOWNLOAD PDF
NEPHROPATHOLOGY QUIZ Unmasked by histology... Filipa Cardoso, Joana Marques, Bernardo Costa, Mário Góis, Helena Sousa, Fernando Nolasco
We present the case of a 78-year-old male, with a known history of benign prostatic hyperplasia, hemorrhoids and paroxysmal atrial fibrillation (AF), with no history of kidney dysfunction.
Port J Nephrol Hypert 2019; 33(1): 61-64 Advance Access publication 29 March 2019 DOWNLOAD PDF
CASE REPORT Fanconi syndrome after Ifosfamide exposure - case report Sónia M. Gomes, Ana M. Garcia, Telma Francisco, Gilda Teixeira, Maria J. Ribeiro, Ana P. Serrão
Ifosfamide is an antineoplastic drug widely used in the treatment of paediatric malignancies.
Port J Nephrol Hypert 2019; 33(1): 49-55 Advance Access publication 27 March 2019 DOWNLOAD PDF
ACKNOWLEDGEMENT OF OUR REVIEWERS A special thank-you to our reviewers A special thank-you to our reviewers
The editors would like to publicly acknowledge the contribution of all our colleagues listed below, who served as reviewers for the Portuguese Journal of Nephrology and Hypertension in the year of 2018.
Port J Nephrol Hypert 2019; 33(1): 81 Advance Access publication 29 March 2019 DOWNLOAD PDF
LETTER TO THE EDITOR Looking for proposals on a new kidney allocation system Bruno A Lima, Helena Alves
The last issue of this journal brought a comment1 on a paper we published here2 in June, 2018. On reading that comment, we felt the need to clarify some of our paper’s conclusions.
Port J Nephrol Hypert 2019; 33(1): 75-76 Advance Access publication 29 March 2019 DOWNLOAD PDF
TUBULAR QUIZ A child with acute kidney injury Rui Domingues, Tânia Moreira, Telma Francisco, Sara Nóbrega, António Pedro Campos, Raul Silva, Margarida Abranches
We present the case of an 18-month-old boy born with intestinal atresia type IIIa, resulting in short bowel syndrome...
Port J Nephrol Hypert 2019; 33(1): 77-79 Advance Access publication 29 March 2019 DOWNLOAD PDF
REVIEW ARTICLE Current guidelines in peritoneal dialysis - Part II Ana Carina Ferreira, Andreia Borges, Cristina Pinto Abreu, Fernando Teixeira e Costa, Marta Pereira, Rui Castro, Sara Barreto, on Behalf of the Peritoneal Dialysis' Study Group of the Portuguese Socie
A successful peritoneal dialysis program depends on knowledge of the current recommendations and on evidence-based practice guidelines.
Port J Nephrol Hypert 2019; 33(1): 37-47 Advance Access publication 25 March 2019 DOWNLOAD PDF
ORIGINAL ARTICLE The role of alteplase in preventing relapsing and repeat peritonitis in peritoneal dialysis Joana M. Martins, Joel Ferreira, Ricardo A. Macau, Fernando T. Costa, Aura Ramos
Introduction: Peritonitis is a common complication in peritoneal dialysis, playing a weighty role in patient morbidity and a major cause of transfer to hemodialysis Relapsing or repeat episodes are... 
Port J Nephrol Hypert 2019; 33(1): 65-68 Advance Access publication 29 March 2019 DOWNLOAD PDF
ORIGINAL ARTICLE Nephrocalcinosis in a portuguese pediatric population Sofia Bota, Joana V. Andrade, Telma Francisco, Raquel Santos, Gisela Neto, Margarida Abranches
Introduction and Aims: Nephrocalcinosis is characterized by the deposition of calcium in the kidney parenchyma and tubules.
Port J Nephrol Hypert 2019; 33(1): 69-73 Advance Access publication 29 March 2019 DOWNLOAD PDF
PERSPECTIVE Pancreas allocation and diabetic end-stage kidney disease Nuno Moreira Fonseca
Transplant options for patients with type 1 diabetes and end-stage kidney disease include deceased donor kidney, live donor kidney, simultaneous pancreas-kidney, pancreas after kidney and islet cell transplantation.
Port J Nephrol Hypert 2019; 33(1): 83-85 Advance Access publication 2 April 2019 DOWNLOAD PDF
CASE REPORT Severe passenger lymphocyte syndrome associated to Rh antibodies after donor living renal transplantation Marika Bini Antunes, Jorge Malheiro, Leonidio Dias, La Salete Martins, Sofia Pedroso, Manuela Almeida, António Castro Henriques, Margarida Amil
The passenger lymphocyte syndrome may cause hemolytic anemia after bone marrow and solid organ transplantation when there is minor erythrocyte antigen incompatibility in the donor/recipient pair.
Port J Nephrol Hypert 2019; 33(2): 83-85 Advance Access publication 8 May 2019 DOWNLOAD PDF
ORIGINAL ARTICLE Kidney dysfunction in renal amyloidosis: does the complement system play a part in hereditary ATTRV30M and iatrogenic ATTR amyloidosis? Ana Carina Ferreira, Fernanda Carvalho, Ana Rita Santos, Fernando Nolasco
Introduction and aims: The complement system may play a part in the pathogenesis of amyloid disorders.
Port J Nephrol Hypert 2019; 33(2): 89-94 Advance Access publication 28 May 2019 DOWNLOAD PDF
ORIGINAL ARTICLE Hepatitis C Virus Core Antigen Test: an HCV RNA screening alternative in end-stage renal disease and hemodialysis? Rita V Alves, Hernâni Gonçalves, Maria L Gonçalves, Karina Lopes, Flora Sofia, Ana V Lobos
Introduction and Aim: Hepatitis C virus screening using anti-HCV antibody is recommended for end-stage renal disease and chronic hemodialysis patients.
Port J Nephrol Hypert 2019; 33(2): 95-98 Advance Access publication 6 June 2019 DOWNLOAD PDF
REVIEW ARTICLE Treatment options for type 2 diabetes mellitus in patientswith chronic kidney disease - old and new drugs Ana Ferreira, Filipa Bastos, Maria Carlos Cordeiro, Jorge Portugal
Chronic kidney disease is highly prevalent in patients with diabetes mellitus.
Port J Nephrol Hypert 2019; 33(2): 99-107 Advance Access publication 6 June 2019 DOWNLOAD PDF
CASE REPORT Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report Nazrul Hassan Jafry, Muhammad Mubarak, Sabiha Anis, Ejaz Ahmed, Fazal Akhtar
We report a case of myeloma-like cast nephropathy in a 27-year-old male patient with human immunodeficiency virus (HIV) infection for 2 years.
Port J Nephrol Hypert 2019; 33(2): 115-118 Advance Access publication 27 June 2019 DOWNLOAD PDF
CASE REPORT IgA dominant glomerulonephritis associated to staphylococcus infection: a peculiar case report Nicole Pestana, Francisca Silva, Pedro Vieira, Ricardo Figueira, José Durães, Gil Silva
IgA dominant glomerulonephritis associated to Staphylococcus infection is a rare clinical entity that has been described mainly in case reports.
Port J Nephrol Hypert 2019; 33(2): 127-130 Advance Access publication 1 July 2019 DOWNLOAD PDF
CASE REPORT Nephronophthisis, a pediatric challenge Ana M. Garcia, Sónia M. Gomes, Telma Francisco, Ana P. Serrão
Nephronophthisis is an autosomal recessive cystic kidney disease characterized by reduced concentrating ability of the kidney, chronic tubulointerstitial nephritis, cystic renal disease and progression to end-stage renal disease.
Port J Nephrol Hypert 2019; 33(2): 109-112 Advance Access publication 26 June 2019 DOWNLOAD PDF
REVIEW ARTICLE Cardiovascular primary prevention - directed approach for individual features Tânia Branco Mano, Sílvia Aguiar Rosa, Pedro Rio, Ana Teresa Timóteo, Rui Cruz Ferreira
Cardiovascular diseases (CVD) remain the leading cause of morbimortality globally.
Port J Nephrol Hypert 2019; 33(2): 119-126 Advance Access publication 27 June 2019 DOWNLOAD PDF
TUBULAR QUIZ Hypokalemia in the setting of acute kidney injury and non-anion gap metabolic acidosis Nuno Moreira Fonseca, Patrícia Alves, David Navarro, João Sousa, Fernando Nolasco
We present a case of a 48-year-old female with past medical history of well-controlled hypertension who was diagnosed with Ewinglike sarcoma, with abdominal wall involvement and pulmonary metastatic lesions.
Port J Nephrol Hypert 2019; 33(2): 139-141 Advance Access publication 4 July 2019 DOWNLOAD PDF
PERSPECTIVE Vascular access for dialysis - the Portuguese experience Carlos Oliveira
Vascular access quality for chronic hemodialysis is a determinant factor in the success of this treatment.
Port J Nephrol Hypert 2019; 33(2): 137-138 Advance Access publication 4 July 2019 DOWNLOAD PDF
COMMENT IgA immune complex deposits, what can lie behind them? Comments on a case of IgA dominant glomerulonephritis associated to staphylococcus infection. Fernanda Carvalho
In this journal Nicole Pestana et al. describe a case of “IgA dominant glomerulonephritis associated to staphylococcus infection”.
Port J Nephrol Hypert 2019; 33(2): 131 Advance Access publication 1 July 2019 DOWNLOAD PDF
NEPHROPATHOLOGY QUIZ An unusual cause of chronic renal dysfunction Maria do Mar Menezes, Patrícia Alves, Aníbal Ferreira, Helena Sousa, Mário Góis, Fernando Nolasco
We present the case of a 41‑year‑old caucasian woman with past medical history of pre‑eclampsia, obesity, cholecystectomy, goiter and chronic kidney disease of unknown etiology diagnosed at age of 21.
Port J Nephrol Hypert 2019; 33(2): 133-136 Advance Access publication 4 July 2019 DOWNLOAD PDF
PERSPECTIVE Nephrology and intervention in the community ? On the need for improving the interplay between nephrology centers and primary care in Portugal Idalina Beirão, Edgar Almeida
Chronic kidney disease is increasing in prevalence, especially among older people.
Port J Nephrol Hypert 2019; 33(2): 113-114 Advance Access publication 26 June 2019 DOWNLOAD PDF
CASE REPORT Cerebral vasculitis - a rare presentation of antineutrophil cytoplasmic antibody associated vasculitis relapse Sara Daniela Rodrigues, Ana Maria Ventura, Daniela Lopes, Susana Pereira, Maria Clara Almeida, Ana Marta Gomes, João Carlos Fernandes
Antineutrophil cytoplasmic antibody (ANCA) associated vasculitis commonly involves kidney, lung, upper respiratory tract, skin, gastrointestinal and occasionally peripheral nervous system.
Port J Nephrol Hypert 2019; 33(1): 3-6 Advance Access publication 18 February 2019 DOWNLOAD PDF
CASE REPORT Crescentic IgA nephropathy associated with pleural tuberculosis Marta R Marques, Pedro R Pereira, Sofia Marques
Crescentic IgA nephropathy represents an aggressive glomerular injury which can cause renal failure unless diagnosed and treated rapidly.
Port J Nephrol Hypert 2019; 33(1): 7-9 Advance Access publication 18 February 2019 DOWNLOAD PDF
REVIEW ARTICLE Membranous nephropathy: an update Hernando Trujillo, Manuel Praga
Great advances have been made in the pathophysiologic and therapeutic areas of membranous nephropathy in the last years.
Port J Nephrol Hypert 2019; 33(1): 10-18 Advance Access publication 18 February 2019 DOWNLOAD PDF
REVIEW ARTICLE Cellular origin and regulation of kidney fibrosis Judith Schimpf, Rafael Kramann
Myofibroblasts take a key position as fibrosis driving, matrix secreting cells in kidney fibrosis and are thought to be important therapeutic targets in chronic kidney disease (CKD).
Port J Nephrol Hypert 2018; 32(3): 279-282 Advance Access publication 31 August 2018 DOWNLOAD PDF
CONSENSUS DOCUMENT Portuguese consensus document statement in diagnostic and management of atypical hemolytic uremic syndrome Ana Azevedo, Bernardo Faria, Catarina Teixeira, Fernanda Carvalho, Gisela Neto, Josefina Santos, Maria do Céu Santos, Nuno Oliveira, Teresa Fidalgo, Joaquim Calado
Among thrombotic microangiopathies (TMA), the hemolytic uremic syndrome associated with dysregulation of the alternative complement pathway (aHUS) is one of the most challenging diseases a nephrologist can face.
Port J Nephrol Hypert 2018; 32(3): 211-232 Advance Access publication 2 October 2018 DOWNLOAD PDF
REVIEW ARTICLE Renal denervation for resistant hypertension: a glimpse of hope on the horizon? Davide Bolignano
Renal denervation by a minimally‑invasive catheter‑based procedure has been extensively studied over the last decade as a powerful tool for treating resistant hypertension, a high‑risk condition the clinical management of which remains a major challenge.
Port J Nephrol Hypert 2018; 32(4): 343-349 Advance Access publication 7 December 2018 DOWNLOAD PDF
COMMENT The Portuguese kidney transplant allocation system - a change is needed Susana Sampaio
Any allocation system should take into account that availability of organs is scarce, implying a fair distribution for maximum efficiency and equality of access while respecting the Leges Artis.
Port J Nephrol Hypert 2018; 32(4): 365-366 Advance Access publication 13 December 2018 DOWNLOAD PDF
COMMENT Kidney biopsy in monoclonal gammopathies Isabel Mesquita, Mário Góis
Several clinical cases have been published in recent issues of PJNH, addressing the monoclonal gammopathies: Immunoglobulin G4‑related disease mimicking multiple myeloma1, Light chain deposition disease: atypical associations in a rare disease2 and What seems most likely may not be the case3.
Port J Nephrol Hypert 2018; 32(4): 399-401 Advance Access publication 4 January 2019 DOWNLOAD PDF
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