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EDITORIAL Fighting glomerular hegemony: giving the renal tubule the credits it deserves Joaquim Calado
This new editorial feature, the tubular quiz, aims at renewing the interest of Portuguese nephrologists in both clinical evaluation and research in renal physiology and disorders that affect the renal tubule.
Port J Nephrol Hypert 2018; 32(1): 9-10 Advance Access publication 5 April 2018 DOWNLOAD PDF
REVIEW ARTICLE The challenge of pregnancy after kidney transplantation Patrícia Cotovio
Kidney transplantation restores the impairment in fertility of end-stage renal disease patients.
Port J Nephrol Hypert 2018; 32(2): 143-148 Advance Access publication 7 June 2018 DOWNLOAD PDF
REVIEW ARTICLE The role of bone biopsy in the management of patients with CKD - MBD C. Belino, C. Meng, L. Pereira, C. Carvalho, R. Neto, Frazão JM
The gold standard for diagnosis and classification of bone disorders is the transiliac crest bone biopsy.
Port J Nephrol Hypert 2018; 32(2): 159-164 Advance Access publication 22 June 2018 DOWNLOAD PDF
ORIGINAL ARTICLE Evaluation of the Portuguese kidney transplant allocation system: comparative results from a simulation Bruno A Lima, Helena Alves
The distribution of such a scarce resource as deceased donor kidneys should be made by observing a balance between fairness, efficiency and flexibility.
Port J Nephrol Hypert 2018; 32(2): 136-142 Advance Access publication 28 June 2018 DOWNLOAD PDF
IN-DEPTH CASE DISCUSSION Making the diagnosis of Alport syndrome and the differential diagnosis of a severe superimposed second glomerulopathy in a young boy João Paulo Oliveira
In a previous issue of this journal, Neves et al.1 reported the occurrence of a severe,  normocomplementemic, acute nephritic syndrome at age 4½ years, in a boy with past medical history of self-limited episodes of macroscopic hematuria associated with respiratory infections, who was eventually diagnosed with Alport syndrome (AS) more than 10 years afterwards.
Port J Nephrol Hypert 2018; 32(2): 110-120 Advance Access publication 28 June 2018 DOWNLOAD PDF
TUBULAR QUIZ An adult patient with hypernatremia: a case of water balance equipoise Nuno Fonseca, Ana Messias, Ana Raquel Garrote, David Navarro, Orlando Cardoso, Fernando Maltez, Joaquim Calado, Fernando Nolasco
A 67‑year‑old black man from Cape Verde was admitted to our emergency department with a two‑day history of altered mental status and fever.
Port J Nephrol Hypert 2018; 32(2): 201-203 Advance Access publication 28 June 2018 DOWNLOAD PDF
CASE REPORT Immunoglobulin G4-related disease mimicking multiple myeloma Marta Sofia Costa, Andreia Silva, Luísa Costa, Ana Rodrigues, Tiago Barra, Sérgio Lemos, Jesús Garrido
Immunoglobulin G4‑related disease (IgG4‑RD) is a rare, poorly understood immune mediated disorder.
Port J Nephrol Hypert 2018; 32(3): 283-288 Advance Access publication 10 September 2018 DOWNLOAD PDF
CASE REPORT Light chain deposition disease: atypical associations in a rare disease Ivo Cunha, Sandra Silva, Rui Henrique, Maximino Costa
Light chain deposition disease is a systemic disorder characterized by deposition of monoclonal light chains in various organs.
Port J Nephrol Hypert 2018; 32(3): 289-292 Advance Access publication 21 September 2018 DOWNLOAD PDF
REVIEW ARTICLE Cellular origin and regulation of kidney fibrosis Judith Schimpf, Rafael Kramann
Myofibroblasts take a key position as fibrosis driving, matrix secreting cells in kidney fibrosis and are thought to be important therapeutic targets in chronic kidney disease (CKD).
Port J Nephrol Hypert 2018; 32(3): 279-282 Advance Access publication 31 August 2018 DOWNLOAD PDF
PERSPECTIVE Transitions of care management in CKD: critical thinking and improving strategies Isabel M Correia, Anabela S Rodrigues
Chronic kidney disease (CKD) has a high clinical and socioeconomic impact and is often associated with multimorbidity.
Port J Nephrol Hypert 2018; 32(3): 233-244 Advance Access publication 27 September 2018 DOWNLOAD PDF
ORIGINAL ARTICLE Nephrolithiasis in a portuguese pediatric population Joana V. Andrade, Sofia Bota, Telma Francisco, Raquel Santos, Gisela Neto, Margarida Abranches
Introduction and Aims: Nephrolithiasis incidence in children has increased considerably. It is associated with substantial morbidity, recurrence and increased adulthood cardiovascular risk and chronic kidney disease.
Port J Nephrol Hypert 2018; 32(3): 258-267 Advance Access publication 27 September 2018 DOWNLOAD PDF
CASE REPORT Intestinal obstruction in a patient on chronic hemodialysis Miguel Bigotte Vieira, Marta Pereira, Cristina Pinto de Abreu
Encapsulating peritoneal sclerosis (EPS) is an uncommon but serious complication of peritoneal dialysis (PD).
Port J Nephrol Hypert 2018; 32(3): 293-298 Advance Access publication 29 September 2018 DOWNLOAD PDF
CONSENSUS DOCUMENT Portuguese consensus document statement in diagnostic and management of atypical hemolytic uremic syndrome Ana Azevedo, Bernardo Faria, Catarina Teixeira, Fernanda Carvalho, Gisela Neto, Josefina Santos, Maria do Céu Santos, Nuno Oliveira, Teresa Fidalgo, Joaquim Calado
Among thrombotic microangiopathies (TMA), the hemolytic uremic syndrome associated with dysregulation of the alternative complement pathway (aHUS) is one of the most challenging diseases a nephrologist can face.
Port J Nephrol Hypert 2018; 32(3): 211-232 Advance Access publication 2 October 2018 DOWNLOAD PDF
CASE REPORT Arterio-arterial graft - an option for hemodialysis patients with exhaustion of venous patrimony Ana Castro, Paulo Almeida, Filipa Silva, Duarte Rego, Joana Tavares, Josefina Santos, Fernanda Silva, José Alexandre Queirós, António Cabrita, Rui Almeida
Introduction: Vascular access (VA) for hemodialysis (HD) is the lifeline for End Stage Renal Disease (ESRD) patients.
Port J Nephrol Hypert 2018; 32(3): 299-304 Advance Access publication 2 October 2018 DOWNLOAD PDF
NEPHROPATHOLOGY QUIZ What seems most likely may not be the case Filipa Cardoso, Joana Marques, Marco Mendes, Mário Góis, Helena Sousa, Fernando Nolasco
A 78-year-old Caucasian woman with a past medical history of hypertension, type 2 diabetes mellitus and dyslipidemia presented to the emergency department with fever (38°C), arterial hypertension (223/98mmHg) and non-bloody diarrhea.
Port J Nephrol Hypert 2018; 32(3): 305-308 Advance Access publication 3 October 2018 DOWNLOAD PDF
TUBULAR QUIZ A diabetic patient with glucosuria Joaquim Calado, Inês Aires, Vasco Fernandes, Fernando Nolasco, José Rueff
FMSB, an individual with type 2 diabetes mellitus (T2D), was referred to our Consulta de Doenças Renais Hereditárias at Hospital de Curry Cabral by his nephrologist, due to a disproportionate amount of glucosuria in light of his metabolic control.
Port J Nephrol Hypert 2018; 32(3): 309-312 Advance Access publication 3 October 2018 DOWNLOAD PDF
CASE REPORT Urinary schistosomiasis: a forgotten and challenging diagnosis Ana C. Castro, André Garrido, Maria J. Brito, Sara Pinto, Vanda Bento
Urinary schistosomiasis is a parasitic disease with a high global burden, especially in poor communities.
Port J Nephrol Hypert 2018; 32(4): 325-329 Advance Access publication 31 October 2018 DOWNLOAD PDF
CASE REPORT Persistent knee pain in a patient with systemic lupus erythematosus Miguel Bigotte Vieira, Joana Monteiro Dias, José Carlos Romeu, Marta Pereira, Cristina Pinto de Abreu
The evaluation of chronic kidney disease-mineral and bone disorder (CKD-MBD) is based on clinical, laboratory, radiology and histological data.
Port J Nephrol Hypert 2018; 32(4): 319-323 Advance Access publication 31 October 2018 DOWNLOAD PDF
REVIEW ARTICLE Renal denervation for resistant hypertension: a glimpse of hope on the horizon? Davide Bolignano
Renal denervation by a minimally‑invasive catheter‑based procedure has been extensively studied over the last decade as a powerful tool for treating resistant hypertension, a high‑risk condition the clinical management of which remains a major challenge.
Port J Nephrol Hypert 2018; 32(4): 343-349 Advance Access publication 7 December 2018 DOWNLOAD PDF
CASE REPORT Membranous nephropathy successfully treated with a Ponticelli regimen in a patient with HIV: do not assume that a well-known secondary cause is the real cause! Meng C, Pereira L, Guedes L, Nunes A, Pereira P, Frazão JM, Pestana M
Idiopathic membranous nephropathy with high-risk criteria for renal disease progression is considered an indication for immunosuppressive treatment.
Port J Nephrol Hypert 2018; 32(4): 331-336 Advance Access publication 7 December 2018 DOWNLOAD PDF
ORIGINAL ARTICLE Infective endocarditis in renal transplant recipients: one center's experience Pereira L, Meng C, Guedes L, Marques S, Nunes A, Sampaio S, Tavares I, Bustorff M, Pestana M
Background: Infective endocarditis (IE) is rarely described among renal transplant recipients.
Port J Nephrol Hypert 2018; 32(4): 337-341 Advance Access publication 7 December 2018 DOWNLOAD PDF
LETTER TO THE EDITOR The transition from pediatric to adult services Marina Vieira, Cecília Silva, Margarida Abranches
Pediatric nephrology diagnoses have specific characteristics, often not well known in the adult nephrological world.
Port J Nephrol Hypert 2018; 32(4): 351-352 Advance Access publication 13 December 2018 DOWNLOAD PDF
CASE REPORT Therapeutic plasma exchange in the treatment of severe hypertriglyceridemia: a case report Tiago J Carvalho, Ana Rita Martins, Rita Calça, João Sousa Torres, Célia Gil, Ilídio Rodrigues, Maria Augusta Gaspar, Teresa Adragão, Margarida Bruges
Severe hypertriglyceridemia is defined as a serum triglyceride level >885mg/dl.
Port J Nephrol Hypert 2018; 32(4): 353-356 Advance Access publication 13 December 2018 DOWNLOAD PDF
ORIGINAL ARTICLE Management of end-stage vascular access failure patients: a retrospective analysis Joana Gameiro, José Agapito Fonseca, Sofia Jorge, José António Lopes
Vascular access (VA) dysfunction is an important cause of morbidity and mortality in the hemodialysis (HD) population.
Port J Nephrol Hypert 2018; 32(4): 357-363 Advance Access publication 13 December 2018 DOWNLOAD PDF
NEPHROPATHOLOGY QUIZ Streamlining diagnosis with urinary sediment microscopy: a case of deteriorating renal function in a kidney transplant patient Nuno Moreira Fonseca, David Navarro, Mário Góis, Helena Sousa, Inês Aires, Fernando Nolasco
We present the case of a 71-year-old Caucasian male with chronic kidney disease secondary to Anti-Neutrophilic Cytoplasmic Autoantibody (ANCA) vasculitis.
Port J Nephrol Hypert 2018; 32(4): 381-384 Advance Access publication 20 December 2018 DOWNLOAD PDF
COMMENT The Portuguese kidney transplant allocation system - a change is needed Susana Sampaio
Any allocation system should take into account that availability of organs is scarce, implying a fair distribution for maximum efficiency and equality of access while respecting the Leges Artis.
Port J Nephrol Hypert 2018; 32(4): 365-366 Advance Access publication 13 December 2018 DOWNLOAD PDF
COMMENT Persistent knee pain in a patient with systemic lupus erythematosus Luciano Pereira
In the present issue of this Journal, Vieira MB et al. reported a case of a female patient with systemic erythematosus lupus with end-stage renal disease.
Port J Nephrol Hypert 2018; 32(4): 367-368 Advance Access publication 20 December 2018 DOWNLOAD PDF
REVIEW ARTICLE Heart failure in chronic kidney disease patients: a summary of non-traditional risk factors Luísa Viveiros, Manuel Pestana
Introduction: Patients with chronic kidney disease are at higher risk of heart failure than the general population.
Port J Nephrol Hypert 2018; 32(4): 369-379 Advance Access publication 20 December 2018 DOWNLOAD PDF
COMMENT Kidney biopsy in monoclonal gammopathies Isabel Mesquita, Mário Góis
Several clinical cases have been published in recent issues of PJNH, addressing the monoclonal gammopathies: Immunoglobulin G4‑related disease mimicking multiple myeloma1, Light chain deposition disease: atypical associations in a rare disease2 and What seems most likely may not be the case3.
Port J Nephrol Hypert 2018; 32(4): 399-401 Advance Access publication 4 January 2019 DOWNLOAD PDF
ORIGINAL ARTICLE Are peritoneal protein losses related to peritonitis risk in patients on peritoneal dialysis? Sara Daniela Rodrigues, Maria Clara Santos, Ana Marta Gomes, João Carlos Fernandes
Background: Peritoneal protein losses (PPL) are an inevitable process in peritoneal dialysis (PD).
Port J Nephrol Hypert 2018; 32(4): 393-398 Advance Access publication 4 January 2019 DOWNLOAD PDF
REVIEW ARTICLE Congenital kidney and urinary tract anomalies: a review for nephrologists Marina Vieira, Aníbal Ferreira, Fernando Nolasco
Kidney and urinary tract development disorder are two of the most prevalent congenital malformations and the main cause of chronic kidney disease in pediatric age patients.
Port J Nephrol Hypert 2018; 32(4): 385-391 Advance Access publication 4 January 2019 DOWNLOAD PDF
TUBULAR QUIZ Hyperkalemia: this time, not the usual suspect Anna Lima, Pedro Campos, Ana Gaspar, Afonso Santos, Patricia Carrilho
A 49-year-old Caucasian male was admitted to the emergency department with a three-day history of abdominal pain and nausea.
Port J Nephrol Hypert 2018; 32(4): 403-405 Advance Access publication 4 January 2019 DOWNLOAD PDF
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