Online First

CASE REPORT Chemical peritonitis associated with intraperitoneal vancomycin:A case series José Silvano, Luciano Pereira, Ana Oliveira, Ana Beco, Miguel Relvas, Rui Silva, Manuel Pestana
Peritonitis is a serious complication in peritoneal dialysis, usually secondary to an infectious cause.
Port J Nephrol Hypert 2021; 35(2): 114-117 Advance Access publication 20 June 2021 DOWNLOAD PDF
CASE REPORT Eosinophilic granulomatosis with polyangiitis with an unusual presentation Rui Filipe Nogueira, Ana Belmira, Vitor Sousa, Rui Alves
Eosinophilic granulomatosis with polyangiitis is an ANCA vasculitis characterized by asthma, rhinosinusitis and peripheral eosinophilia.
Port J Nephrol Hypert 2021; 35(2): 118-122 Advance Access publication 28 June 2021 DOWNLOAD PDF
CASE REPORT The use of hemodialysis in hypercalcemic crisis secondary to primary hyperparathyroidism Catarina Nazário Marouço, Fernando Caeiro, Bernardo Marques da Costa, David Navarro, Rita Magriço, Fernando Nolasco
Severe hypercalcemia can be either acute or decompensate from a chronic state to a medical emergency, the hypercalcemic crisis.
Port J Nephrol Hypert 2021; 35(2): 123-127 Advance Access publication 28 June 2021 DOWNLOAD PDF
ORIGINAL ARTICLE The very elderly followed at a nephrology center: metabolic acidosis as a predictor of progressive chronic kidney disease Marina Reis, Catarina Almeida, Catarina Ribeiro, Daniela Alferes, Ana Marta Gomes, João Carlos Fernandes
Chronic kidney disease is an increasingly common diagnosis in the very elderly and identifying the patients who benefit from a nephrologist’s intervention and the ones who would not might avoid wasteful or harmful interventions.
Port J Nephrol Hypert 2021; 35(2): 84-88 Advance Access publication 20 June 2021 DOWNLOAD PDF
REVIEW ARTICLE Immature hemodialysis arteriovenous fistulas: What should we aim for? Rui F. Silva, Hugo Diniz, Miguel Relvas, José Silvano, Ana Malheiro, Luís Coentrão
Arteriovenous fistulas (AVFs) are the first-choice vascular access for most HD patients. Up to 60% of AVFs do not mature adequately, mostly due to stenosis.
Port J Nephrol Hypert 2021; 35(2): 106-110 Advance Access publication 20 June 2021 DOWNLOAD PDF
REVIEW ARTICLE Mineral and bone disease in renal transplantation Ana Carina Ferreira, Aníbal Ferreira
Chronic kidney disease – mineral and bone disorders (CKD‑MBD) tends to improve or to change phenotypically in the post‑transplant period.
Port J Nephrol Hypert 2021; 35(2): 111-113 Advance Access publication 20 June 2021 DOWNLOAD PDF
REVIEW ARTICLE Sarcopenia in chronic kidney disease - A brief review Beatriz Donato, Catarina Teixeira, Sónia Velho, Edgar Almeida
Sarcopenia is a progressive age‑related loss of muscle mass associated with a decline in muscle function and physical performance.
Port J Nephrol Hypert 2021; 35(2): 99-105 Advance Access publication 20 June 2021 DOWNLOAD PDF
ORIGINAL ARTICLE Peritoneal access - a pressing problem Patrícia Valério, Maria João Carvalho, Olívia Santos, António Cabrita, Anabela Rodrigues
In Portugal, as well as in Europe, peritoneal dialysis (PD) use remains low.
Port J Nephrol Hypert 2021; 35(2): 89-92 Advance Access publication 8 July 2021 DOWNLOAD PDF
NEPHROPATHOLOGY QUIZ Isolated microscopic hematuria: a world of possibilities Anna Lima, Afonso Santos, Ana Catarina Brás, Rita Theias, Patrícia Carrilho, Pedro Campos
We present the case of a 41-year-old South American female who was referred for nephrological evaluation due to persistent microscopic hematuria.
Port J Nephrol Hypert 2021; 35(2): 128-130 Advance Access publication 29 June 2021 DOWNLOAD PDF
PERSPECTIVE Surgical role in the management of peritoneal dialysis catheters - evidence and proposals to improve current practices Rita Vicente, Rui Silva, Ricardo Santos, Anabela Rodrigues, Manuel Amoedo
Peritoneal dialysis (PD) relies on adequate function of PD catheter.
Port J Nephrol Hypert 2021; 35(2): 69-74 Advance Access publication 29 june 2021 DOWNLOAD PDF
PERSPECTIVE Why the incidence in dialysis in the Lisbon and Tagus Valley Region (LVTR) is two to three times higher than in other regions of the country M. Martins Prata
The analysis of data from the Ministry of Health’s Integrated Chronic Kidney Disease Management Platform (PI‑GID), reveals the existence of a striking regional difference in the incidence in dialysis.
Port J Nephrol Hypert 2021; 35(2): 75-81 Advance Access publication 29 June 2021 DOWNLOAD PDF
PERSPECTIVE Reflections on the portuguese nephrology fellowship program in 2021. Nephrology fellowship training at a crossroads Artur Mendes
Nephrology is facing a period of remarkable and unprecedented change.
Port J Nephrol Hypert 2021; 35(2): 82-83 Advance Access publication 29 June 2021 DOWNLOAD PDF
ORIGINAL ARTICLE Is COVID-19 that different in hemodialysis patients?: A single-center experience Marina Reis, Catarina Almeida, Ana Ventura, Catarina Ribeiro, Ana Marta Gomes, Daniela Lopes, Clara Santos, Sónia Sousa, João Carlos Fernandes
Coronavirus disease 2019 (COVID-19) has affected millions worldwide, and in particular the care of patients on maintenance hemodialysis.
Port J Nephrol Hypert 2021; 35(2): 93-98 Advance Access publication 29 June 2021 DOWNLOAD PDF
LETTER TO THE EDITOR The golden generation in Portuguese nephrology: fact or fiction? Marco Mendes
The score of 19 has become trivialized during Nephrology residence evaluation or as a final exam grade for some time.
Port J Nephrol Hypert 2021; 35(2): 131 Advance Access publication 29 June 2021 DOWNLOAD PDF
REVIEW ARTICLE End stage kidney disease in the elderly: Hope for the best Patrícia Valério, Ana Farinha
With an increased number of aged chronic kidney disease (CKD) patients, along with medical and technological advances, the options to approach end‑stage kidney disease (ESKD) have multiplied.
Port J Nephrol Hypert 2020; 34(4): 225-232 Advance Access publication 21 December 2020 DOWNLOAD PDF
ORIGINAL ARTICLE A cost-effective analysis of drug-eluting balloon in highly recurrent stenosis on dialysis vascular access Telmo Carvalho, Dulce Carvalho, Patrícia Marujo, Maria David, João Cruz, Pedro Maia, Pedro Ponce
Background: The efficacy and cost-effectiveness of drug-eluting balloon (DEB) in vascular access for dialysis remain unclear.
Port J Nephrol Hypert 2020; 34(4): 211-216 Advance Access publication 6 January 2021 DOWNLOAD PDF
REVIEW ARTICLE Extracorporeal light chains removal - What role does this play in 2020? Inês Coelho, Hugo Ferreira, Teresa Chuva, Ana Paiva, José Maximino
Multiple Myeloma (MM) is characterized by a neoplastic proliferation of plasma cell clones producing monoclonal immunoglobulin.
Port J Nephrol Hypert 2020; 34(4): 233-238 Advance Access publication 6 January 2021 DOWNLOAD PDF
CASE REPORT Clinical perspectives to improve pregnancy outcome in women undergoing chronic hemodialysis Luiz Paulo José Marques, Regina Rocco, Paulo Roberto Silva Marinho, Eugênio Pacelle Queiroz Madeira, Lygia Maria Soares Fernandes Vieira
Severe Chronic Kidney Disease is considered a powerful method of contraception per se, and pregnancy among women undergoing chronic hemodialysis is a rare event.
Port J Nephrol Hypert 2020; 34(4): 244-247 Advance Access publication 6 January 2021 DOWNLOAD PDF
PERSPECTIVE A quest for improving the quality and utility of the individual registry of patients starting renal replacement therapy in Portugal Edgar A F de Almeida, Anabela Rodrigues
Portugal has one of the highest rates of prevalence and incidence of dialysis in Europe.
Port J Nephrol Hypert 2020; 34(4): 193-194 Advance Access publication 21 December 2020 DOWNLOAD PDF
PERSPECTIVE The rediscovery of nephropathology with artificial intelligence Luís Rodrigues, Pinaki Sarder, Kuang-Yu Jen, Brandon Ginley, Jorge Pratas, Vitor Sousa, Arnaldo Figueiredo, Rui Alves
A kidney biopsy is a beloved tool for most nephrologists. It is as old as nephrology itself, and for the last fifty years, it has helped us to understand the pathophysiology of kidney disease and offer the best care to our patients.
Port J Nephrol Hypert 2020; 34(4): 195-197 Advance Access publication 6 January 2021 DOWNLOAD PDF
PERSPECTIVE Ultrasound in vascular access management ? How to start and enhance a comprehensive program Tiago Assis Pereira
Diagnostic medicine has evolved from a solely physical examination to a setting where a diversity of complementary diagnostic methods is applied.
Port J Nephrol Hypert 2020; 34(4): 198-203 Advance Access publication 6 January 2021 DOWNLOAD PDF
NEPHROPATHOLOGY QUIZ Hepatitis B virus infection and the kidney: a wide range of manifestations Rui Barata, Patrícia Alves, Tiago Assis Pereira, Mário Góis, Helena Viana, Fernando Nolasco
We present a case of a 46-year-old African male referred for chronic kidney disease.
Port J Nephrol Hypert 2020; 34(4): 248-250 Advance Access publication 6 January 2021 DOWNLOAD PDF
TUBULAR QUIZ A case of polyuria Joaquim Calado
We present the case of a 39‑year‑old woman referred to the nephrology outpatient unit with polyuria (daily urinary output of 12 L).
Port J Nephrol Hypert 2020; 34(4): 251-253 Advance Access publication 6 January 2021 DOWNLOAD PDF
ORIGINAL ARTICLE In-hospital and one-year mortality among patients with acute kidney injury and hematological malignancies Inês Coelho, Teresa Chuva, Hugo Ferreira, Ana Paiva, José M. Costa
Hematological malignancies (HM) confer a high risk of acute kidney injury (AKI), which is associated with elevated morbi-mortality.
Port J Nephrol Hypert 2021; 35(1): 11-17 Advance Access publication 14 April 2021 DOWNLOAD PDF
CASE REPORT Acute hyperammonemic encephalopathy - an indication for an extracorporeal depuration technique A case report and literature review Filipa Silva, Joana Tavares, Ana Castro, Arlindo Guimas, Cristina Freitas, João Pedro Pimentel, António Cabrita
Introduction: Ammonia is a resultant molecule from the protein metabolism that can be neurotoxic when present in high concentrations, causing brain edema and encephalopathy.
Port J Nephrol Hypert 2021; 35(1): 43-46 Advance Access publication 14 April 2021 DOWNLOAD PDF
ORIGINAL ARTICLE Prognostic value of lymphocyte cell ratios in peritoneal dialysis Roberto C. Marques, Eduarda C. Carias, Ana T. Domingos, Anabela M. Guedes, Idalécio Bernardo, Pedro L. Neves
Background: Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) have been introduced as useful inflammatory markers to predict the outcome of a wide spectrum of diseases, such as malignancies and cardiovascular pathologies.
Port J Nephrol Hypert 2021; 35(1): 18-21 Advance Access publication 14 April 2021 DOWNLOAD PDF
CASE REPORT A case of lupus podocytopathy and a review of the literature José Silvano, Augusta Praça, Inês Castro Ferreira, Ana Teresa Nunes, Pedro Rodrigues-Pereira, Roberto Pestana Silva, Susana Sampaio, Manuel Pestana
Nephrotic syndrome in systemic lupus erythematosus patients with histological evidence of minimal change disease, mesangial proliferation or focal and segmental glomerulosclerosis on light microscopy, represents a distinct clinical entity – lupus podocytopathy
Port J Nephrol Hypert 2021; 35(1): 39-42 Advance Access publication 14 Abril 2021 DOWNLOAD PDF
REVIEW ARTICLE High serum bicarbonate and adverse outcomes in hemodialysis patients Gonçalo Ávila, Ivo Laranjinha, Patrícia Matias
Metabolic acidosis is a usual complication of progressive chronic kidney disease and is associated with morbidity and mortality. The correction of metabolic acidosis is a main goal of dialysis.
Port J Nephrol Hypert 2021; 35(1): 35-38 Advance Access publication 14 April 2021 DOWNLOAD PDF
CASE REPORT Systemic lupus erythematosus and ANCA-associated vasculitis overlap syndrome: A case report and literature review of poliautoimmunity Ana Gaspar, Anna Lima, Afonso Santos, Catarina Brás, Rita Theias Manso, Karina Soto
Systemic lupus erythematosus and ANCA-associated vasculitis overlap syndrome is rare and complex.
Port J Nephrol Hypert 2021; 35(1): 47-50 Advance Access publication 14 April 2021 DOWNLOAD PDF
NEPHROPATHOLOGY QUIZ Kidney graft dysfunction in a patient with SARS-CoV-2 pneumonia - Not everything is COVID 19 Cátia Figueiredo, Patrícia Valério, Helena Sousa, Mário Góis, Fernando Nolasco
We present a case of a 46-year-old African male with chronic kidney disease secondary to hypertensive nephropathy, in hemodialysis for five years.
Port J Nephrol Hypert 2021; 35(1): 59-62 Advance Access publication 15 April 2021 DOWNLOAD PDF
ORIGINAL ARTICLE The role of incremental peritoneal dialysis among patients on peritoneal dialysis. A longitudinal analysis over 20 years Joana Eugénio Santos, Rui Silva, Rita Vicente, Iolanda Santos, Miguel Coimbra, David Fiel, Manuel Amoedo, Carlos Pires
Background: There is an ongoing increasing focus on person‑centered individualized dialysis prescription.
Port J Nephrol Hypert 2021; 35(1): 22-28 Advance Access publication 14 April 2021 DOWNLOAD PDF
ORIGINAL ARTICLE Fabry disease in patients under dialysis: A screening study and identification of a novel mutation Francisca Gomes da Silva, Nicole Pestana, José Durães, Nuno Guimarães Rosa, Gil Silva
Fabry disease (FD) is a rare systemic disease, with a large spectrum of disease severity.
Port J Nephrol Hypert 2021; 35(1): 29-34 Advance Access publication 14 April 2021 DOWNLOAD PDF
PERSPECTIVE Portuguese Nephrology: We can be greener Diogo Francisco, Ivo Laranjinha
Healthcare facilities are among the greatest contributors to resource consumption and waste generation.
Port J Nephrol Hypert 2021; 35(1): 6-10 Advance Access publication 14 April 2021 DOWNLOAD PDF
CASE REPORT Lupus nephritis with an unusual histopathological pattern Marcelo Aveiro, Nicole Pestana, Francisca Silva, Pedro Vieira, Nuno Rosa, Gil Silva
Introduction: Systemic lupus erythematosus (SLE) is an autoimmune disease that can affect multiple organs.
Port J Nephrol Hypert 2021; 35(1): 51-54 Advance Access publication 15 April 2021 DOWNLOAD PDF
CASE REPORT The misleading laboratory results: Renal impairment associated with high anti myeloperoxidase titer (anti-MPO) does not always mean ANCA vasculitis Mariana Sousa, Cristina Santos, Rita Gouveia, Fernando Pereira, Rita Manso, Jorge Silva
Introduction: Antineutrophil cytoplasmic autoantibodies (ANCAs) are crucial in the pathogenesis of ANCA-associated glomerulonephritis.
Port J Nephrol Hypert 2021; 35(1): 55-58 Advance Access publication 15 April 2021 DOWNLOAD PDF
PERSPECTIVE Nephrolithiasis is not a stone in the nephrologist's shoe Ivo Laranjinha, Jorge Dickson
The prevalence of kidney stones (KS) is increasing and occurring sooner in life.
Port J Nephrol Hypert 2021; 35(1): 3-5 Advance Access publication 14 April 2021 DOWNLOAD PDF
LETTER TO THE EDITOR Incidence in dialysis and chronic kidney disease prevalencein the Portuguese population M. Martins Prata
Portugal has the highest incidence of dialysis in Europe and one of the highest in the world. 
Port J Nephrol Hypert 2021; 35(1): 63 Advance Access publication xx April 2021 DOWNLOAD PDF